3-Hydroxy-2-Oxo Sumatriptan (INR 34900/- 50 mg, in stock)
Catalogue No:
ACT-S002003
Common name:
3-Hydroxy-2-Oxo Sumatriptan (USP)
CAS:
2250254-19-2
Mol. Weight:
327.4
Rel. CAS No
- NA
Shipping Condition
Ambient
Product Overview
Chemical Name:
1-{3-[2-(Dimethylamino)ethyl]-3-hydroxy-2-oxoindolin-5-yl}-N-methylmethanesulfonamide
Shipping Temperature:
Ambient
HSN Code:
38229010
Country of Origin:
India
Smiles:
O=S(CC1=CC=C2C(C(CCN(C)C)(O)C(N2)=O)=C1)(NC)=O
Description
3-Hydroxy-2-Oxo Sumatriptan (CAS 2250254-19-2), designated in the USP, is a pharmaceutical impurity reference standard related to sumatriptan, molecular formula C14H21N3O4S, molecular weight 327.4, chemically 1-{3-[2-(Dimethylamino)ethyl]-3-hydroxy-2-oxoindolin-5-yl}-N-methylmethanesulfonamide. Sumatriptan is a serotonin 5-HT1 receptor agonist used to treat migraine. Allas Chem Tech is a manufacturer and supplier of pharmaceutical reference standards based in Bangalore, India, and holds this sumatriptan impurity in stock in 50 mg packs at Rs.34900/-, supplied with a certificate of analysis and complete characterisation data.
Specifications
| Field | Value |
|---|---|
| Catalogue No. | ACT-S002003 |
| CAS No. | 2250254-19-2 |
| Chemical Name (USP) | 1-{3-[2-(Dimethylamino)ethyl]-3-hydroxy-2-oxoindolin-5-yl}-N-methylmethanesulfonamide |
| Mol. Formula | C14H21N3O4S (computed from the SMILES on the live Allas page) |
| Mol. Weight | 327.4 g/mol |
| Parent API | Sumatriptan |
| Product Category | Impurity Reference Standard |
| Pack Size | 50 mg |
| Price | Rs.34900/- per 50 mg |
| Stock Status | In Stock |
| SMILES | O=S(CC1=CC=C2C(C(CCN(C)C)(O)C(N2)=O)=C1)(NC)=O |
| Shipping | Ambient |
| HSN Code | 38229010 |
| Country of Origin | India |
Analytical applications
3-Hydroxy-2-Oxo Sumatriptan is used in analytical method development and method validation (AMV), and in Quality Control (QC) applications supporting ANDA and DMF submissions for sumatriptan.
Oxidative degradation marker
The 3-hydroxy-2-oxoindolin core reflects oxidation at the indole 3-position of sumatriptan, a known degradation and process-related pathway for the parent molecule. A characterised standard for this oxidised form supports stability-indicating method validation as much as routine release testing.
Quality control and regulatory filings
The standard supports routine QC release testing of sumatriptan drug substance and drug product, and is used to generate impurity data submitted in regulatory filings. Full characterisation data accompanies every batch.
Documentation supplied
Every order of 3-Hydroxy-2-Oxo Sumatriptan ships with a Certificate of Analysis (COA), 1H NMR, 13C NMR, Mass/LC-MS, HPLC, FT-IR and TGA potency data. An MSDS and a Structure Elucidation Report are available on request.
Synonyms and alternate designations
The following describes the same material, CAS 2250254-19-2.
1-{3-[2-(Dimethylamino)ethyl]-3-hydroxy-2-oxoindolin-5-yl}-N-methylmethanesulfonamide
Frequently asked questions
What is the CAS number of 3-Hydroxy-2-Oxo Sumatriptan?
The CAS number is 2250254-19-2.
Which drug is this an impurity of?
It is a Sumatriptan impurity. Sumatriptan is a triptan used to treat acute migraine attacks.
What causes this impurity to form?
It reflects oxidation at the 3-position of the parent indole ring, a known degradation pathway for sumatriptan.
What is the molecular formula and weight?
The molecular formula is C14H21N3O4S and the molecular weight is 327.4 g/mol.
Where can I buy 3-Hydroxy-2-Oxo Sumatriptan?
Allas Chem Tech supplies it directly from our Bangalore facility. It is in stock in 50 mg packs at Rs.34900/-, shipped at ambient temperature.
What documentation is included?
COA, MSDS, NMR, Mass, HPLC, IR and TGA potency data, with a Structure Elucidation Report available on request.
