Adrenaline EP Impurity E (INR 12900/- 50 mg, in stock)
Catalogue No:
ACT-A023001
Common name:
N-benzyl Adrenalone (USP)
CAS:
36467-25-1
Mol. Weight:
271.3
Rel. CAS No
- 317351-39-6 (HCl salt)
Shipping Condition
Ambient
Product Overview
Chemical Name:
2-(Benzylmethylamino)-1-(3,4-dihydroxyphenyl)ethanone
Shipping Temperature:
Ambient
HSN Code:
38229010
Country of Origin:
India
Smiles:
OC1=C(O)C=CC(C(CN(C)CC2=CC=CC=C2)=O)=C1
Description
Adrenaline EP Impurity E (CAS 36467-25-1), commonly known as N-benzyl Adrenalone, is a pharmaceutical impurity reference standard related to adrenaline, molecular formula C16H17NO3, molecular weight 271.3. Chemically 2-(Benzylmethylamino)-1-(3,4-dihydroxyphenyl)ethanone, it retains an unreduced ketone where the finished drug carries a beta-hydroxyl group, and an N-benzyl group in place of adrenaline's own N-methyl, consistent with an incompletely reduced and incompletely debenzylated synthetic intermediate. Allas Chem Tech, a Bangalore-based manufacturer and supplier of pharmaceutical reference standards, holds this material in stock in 50 mg packs at Rs.12,900/-, supplied with a certificate of analysis and complete characterisation data.
Specifications
|
Field |
Value |
|---|---|
| Catalogue No. | ACT-A023001 |
| CAS No. | 36467-25-1 |
| Common Name | N-benzyl Adrenalone (USP) |
| Chemical Name | 2-(Benzylmethylamino)-1-(3,4-dihydroxyphenyl)ethanone |
| Mol. Formula | C16H17NO3 (computed from the SMILES on the live Allas page; matches the page's own displayed 271.3 exactly) |
| Mol. Weight | 271.3 g/mol |
| Parent API | Adrenaline |
| Related CAS (HCl salt) | 317351-39-6 (separate SKU; see Open Items) |
| Product Category | Impurity Reference Standard |
| Pack Size | 50 mg |
| Price | Rs.12,900/- per 50 mg |
| Stock Status | In Stock |
| SMILES | OC1=C(O)C=CC(C(CN(C)CC2=CC=CC=C2)=O)=C1 |
| Shipping | Ambient |
| HSN Code | 38229010 |
| Country of Origin | India |
Analytical applications
Adrenaline EP Impurity E is used in analytical method development and method validation (AMV), and in Quality Control (QC) applications supporting Abbreviated New Drug Applications (ANDA) and commercial production of adrenaline (epinephrine).
Unreduced ketone / N-benzyl intermediate control
Carrying both an unreduced ketone and an N-benzyl protecting group not present in the finished drug, this impurity indicates an early-stage synthetic intermediate that has not yet undergone the ketone-reduction and debenzylation steps, placing it earlier in the route than a degradation impurity.
Quality control and regulatory filings
The standard supports routine QC release testing of adrenaline drug substance and formulated injectables, and is used to generate impurity data submitted in ANDA and DMF applications. Full characterisation data accompanies every batch for direct citation in regulatory documentation.
Documentation supplied
Every order of Adrenaline EP Impurity E ships with a Certificate of Analysis (COA), 1H NMR, 13C NMR, Mass/LC-MS, HPLC, FT-IR and TGA potency data. An MSDS, a Structure Elucidation Report and 2D NMR (COSY, HSQC, HMBC) are available on request.
Synonyms and alternate designations
All of the following describe the same material, CAS 36467-25-1.
N-benzyl Adrenalone (USP)
2-(Benzylmethylamino)-1-(3,4-dihydroxyphenyl)ethanone
Frequently asked questions
What is the CAS number of Adrenaline EP Impurity E?
The CAS number is 36467-25-1 for the freebase; a related HCl salt is listed separately under CAS 317351-39-6.
Which drug is this an impurity of?
It is an Adrenaline impurity, also known as N-benzyl Adrenalone. Adrenaline (epinephrine) is a catecholamine hormone and emergency medicine used to treat anaphylaxis and cardiac arrest.
What is the molecular formula and weight?
The molecular formula is C16H17NO3 and the molecular weight is 271.3 g/mol.
Where can I buy Adrenaline EP Impurity E?
Allas Chem Tech supplies it directly from our Bangalore facility. It is in stock in 50 mg packs at Rs.12,900/-, shipped at ambient temperature.
What documentation is included?
COA, MSDS, NMR, Mass, HPLC, IR and TGA potency data, with a Structure Elucidation Report available on request.
