Cyclohexanone Propanal Derivative Isomer 1&2 (INR 59900/- 50 mg, in stock)

Cyclohexanone Propanal Derivative Isomer 1&2 (CAS 2989438-72-2) is an Artemether impurity reference standard, molecular formula C14H22O3, molecular weight 238.32. Designated in the USP as 2-(4-Methyl-2-oxo-3-(3-oxobutyl)cyclohexyl)propanal, it is supplied as a mixture of diastereomers, which is what the "Isomer 1&2" designation refers to. Allas Chem Tech is a manufacturer and supplier of pharmaceutical reference standards based in Bangalore, India, and holds this Artemether impurity in stock in 50 mg packs at Rs.59900/-, supplied with a certificate of analysis and complete characterisation data.

Specifications

Catalogue No.: ACT-A025001
CAS No.: 2989438-72-2
Chemical Name (USP): 2-(4-Methyl-2-oxo-3-(3-oxobutyl)cyclohexyl)propanal
Mol. Formula: C14H22O3
Mol. Weight: 238.32 g/mol
Parent API: Artemether
Product Category: Impurity Reference Standard
Pack Size: 50 mg
Price: Rs.59900/- per 50 mg
Stock Status: In Stock
Shipping: Ambient
HSN Code: 38229010
Country of Origin: India

Analytical applications

This Artemether impurity reference standard is used in analytical method development and method validation (AMV), and in Quality Control (QC) applications supporting Abbreviated New Drug Applications (ANDA) and commercial production of artemether. Traceability against pharmacopeial standards, USP or EP, can be provided subject to feasibility.

Method development and validation

Because the material is supplied as a mixture of diastereomers, it is particularly useful in establishing chromatographic resolution between the two isomers. Co-elution at this stage would mask the true impurity level, so resolving the diastereomer pair is a defined objective during method development rather than an incidental check.

Quality control and regulatory filings

The standard supports routine QC release testing of artemether drug substance and drug product, and is used to generate the impurity data submitted in ANDA and DMF applications. Full characterisation data accompanies every batch, so the reference standard can be cited directly in regulatory documentation.

Documentation supplied

Every order of Cyclohexanone Propanal Derivative Isomer 1&2 ships with a Certificate of Analysis (COA), 1H NMR, 13C NMR, Mass/LC-MS, HPLC, FT-IR and TGA potency data. An MSDS, a Structure Elucidation Report and 2D NMR (COSY, HSQC, HMBC) are available on request.

Synonyms and alternate designations

Buyers and pharmacopoeias refer to this Artemether impurity under several names. All of the following describe the same material, CAS 2989438-72-2.

Cyclohexanone Propanal Derivative Isomer 1&2 (USP)

Cyclohexanone Propanal Derivative (Isomer 1 + Isomer 2)

Cyclohexanone Propanal Derivative (Mixture of Diastereomers)

2-(4-Methyl-2-oxo-3-(3-oxobutyl)cyclohexyl)propanal

Artemether Cyclohexanone Impurity

Frequently asked questions

What is the CAS number of Cyclohexanone Propanal Derivative Isomer 1&2?

The CAS number is 2989438-72-2.

 Which drug is this an impurity of?

It is an Artemether impurity. Artemether is an artemisinin-derived antimalarial used in combination therapy, most commonly with lumefantrine.

Why is it supplied as a mixture of diastereomers?

The compound is produced as two diastereomers. Both are relevant to impurity profiling, so the reference standard is supplied as the mixture rather than as separated isomers.

What is the molecular formula and weight?

The molecular formula is C14H22O3 and the molecular weight is 238.32 g/mol.

Where can I buy Cyclohexanone Propanal Derivative Isomer 1&2?

Allas Chem Tech supplies it directly from our Bangalore facility. It is in stock in 50 mg packs at Rs.59900/-, shipped at ambient temperature.

What documentation is included?

COA, MSDS, NMR, Mass, HPLC, IR and TGA potency data, with a Structure Elucidation Report available on request.