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D-[Phe]-6-Semaglutide ( INR 99000/- 50 mg, 5-6 weeks)
Catalogue No:
ACT-S007005
Common name:
H-His-Aib-Glu-Gly-Thr-D-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Gly-Gln-Gln-Ala-Ala-Lys-(AEEAc-AEEAc-Gamma-Glu-17-carboxy heptadecanoyl)-Glu-Phe-lle-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH
CAS:
NA
Mol. Weight:
4113.64
Rel. CAS No
- NA
Shipping Condition
cold shipment
Product Overview
Chemical Name:
(3S,9S,12R,15S,18S,21S,24S,27S,30S,33S,36S,39S,45S,48S,51S,54S,81R)-54-(((6S,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-Indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-45-(3-amino-3-oxopropyl)-12-benzyl-39-(2-carboxyethyl)-21-(carboxymethyl)-33-(4-hydroxybenzyl)-9,15-bis((R)-1-hydroxyethyl)-18,27,30-tris(hydroxymethyl)-36-isobutyl-24-isopropyl-48,51-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,60,69,78,83-henicosaoxo-62,65,71,74-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,59,68,77,82-henicosaazanonanonacontane-1,81,99-tricarboxylic Acid
Shipping Temperature:
cold shipment
HSN Code:
38229010
Country of Origin:
India
Smiles:
Description
D-[Phe]-6-Semaglutide is a pharmaceutical impurity reference standard related to Semaglutide, molecular formula C187H291N45O59, molecular weight 4113.64. Identified industry-wide by amino-acid sequence rather than by a CAS number. Sequence: H-His-Aib-Glu-Gly-Thr-D-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Gly-Gln-Gln-Ala-Ala-Lys-(AEEAc-AEEAc-Gamma-Glu-17-carboxy heptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Allas Chem Tech, a Bangalore-based manufacturer and supplier of pharmaceutical reference standards, carries this material in 50 mg packs at Rs.99000/-, supplied with a certificate of analysis and complete characterisation data.
Specifications
| Field | Value |
|---|---|
| Catalogue No. | Pending (client SKU — not available without live-site access) |
| CAS No. | Not assigned (standard for peptide-related substances; identified by sequence) |
| Amino Acid Sequence | H-His-Aib-Glu-Gly-Thr-D-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Gly-Gln-Gln-Ala-Ala-Lys-(AEEAc-AEEAc-Gamma-Glu-17-carboxy heptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH |
| Chemical Name | Identified industry-wide by amino-acid sequence rather than by a CAS number. Sequence: H-His-Aib-Glu-Gly-Thr-D-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Gly-Gln-Gln-Ala-Ala-Lys-(AEEAc-AEEAc-Gamma-Glu-17-carboxy heptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. |
| Mol. Formula | C187H291N45O59 |
| Mol. Weight | 4113.64 |
| Parent API | Semaglutide |
| Product Category | Impurity Reference Standard |
| Pack Size | 50 mg |
| Price | Rs.99000/- per 50 mg |
| Stock Status | Ships in 5-6 Weeks |
| SMILES | Not published by third-party sources consulted |
| Shipping | Ambient |
| HSN Code | 38229010 |
| Country of Origin | India |
Analytical applications
D-[Phe]-6-Semaglutide is used in analytical method development and method validation (AMV), and in Quality Control (QC) applications supporting Abbreviated New Drug Applications (ANDA) and commercial production of semaglutide.
D-amino-acid chiral-inversion impurity (position 6); thinner single-source corroboration
Sequence, formula and MW sourced from 1 independent source (Pharmaffiliates) -- thinner corroboration than most rows in this job, recommend a follow-up verification pass. A D-amino-acid chiral-inversion impurity at position 6 (Phe to D-Phe), part of the same degradant class as row 249. Formula and MW are identical to parent Semaglutide, consistent with every other single-point D-isomer impurity in this 11-row run (244-254).
Quality control and regulatory filings
The standard supports routine QC release testing of semaglutide drug substance and drug product, and is used to generate impurity data submitted in ANDA and DMF applications. Full characterisation data accompanies every batch for direct citation in regulatory documentation.
Documentation supplied
Every order of D-[Phe]-6-Semaglutide ships with a Certificate of Analysis (COA), 1H NMR, 13C NMR, Mass/LC-MS, HPLC, FT-IR and TGA potency data. An MSDS, a Structure Elucidation Report and 2D NMR (COSY, HSQC, HMBC) are available on request.
Synonyms and alternate designations
All of the following describe the same material (CAS not yet assigned).
- Amino-acid sequence: H-His-Aib-Glu-Gly-Thr-D-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Gly-Gln-Gln-Ala-Ala-Lys-(AEEAc-AEEAc-Gamma-Glu-17-carboxy heptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH
Frequently asked questions
What is the CAS number of D-[Phe]-6-Semaglutide?
D-[Phe]-6-Semaglutide does not currently have an assigned CAS Registry Number; it is identified industry-wide by amino-acid sequence rather than CAS number.
Which drug is this an impurity of?
It is a Semaglutide impurity.
What is the molecular formula and weight?
The molecular formula is C187H291N45O59 and the molecular weight is 4113.64.
Where can I buy D-[Phe]-6-Semaglutide?
Allas Chem Tech supplies it directly from our Bangalore facility. D-[Phe]-6-Semaglutide is listed at Rs.99000/- per 50 mg for a 50 mg pack; current availability per the product URL slug is ships in 5-6 weeks.
What documentation is included?
COA, MSDS, NMR, Mass, HPLC, IR and TGA potency data, with a Structure Elucidation Report available on request.
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