D-[Ser]-11-Semaglutide

D-[Ser]-11-Semaglutide (INR 99000/- 50 mg, 5-6 weeks)

Catalogue No:

ACT-S007002

Common name:

H-Aib-EGTFTSDV{d-S}SYLEGQAAK(18Oct-Gamma-Glu-AEEA-AEEA)EFIAWLVRGRG

CAS:

NA

Mol. Weight:

4113.60

Rel. CAS No

  • NA

Shipping Condition

cold shipment

Product Overview

Chemical Name:

(3S,9S,12S,15S,18S,21S,24S,27R,30S,33S,36S,39S,45S,48S,51S,54S,81R)-54-(((6S,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-45-(3-amino-3-oxopropyl)-12-benzyl-39-(2-carboxyethyl)-21-(carboxymethyl)-33-(4-hydroxybenzyl)-9,15-bis((R)-1-hydroxyethyl)-18,27,30-tris(hydroxymethyl)-36-isobutyl-24-isopropyl-48,51-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,60,69,78,83-henicosaoxo-62,65,71,74-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,59,68,77,82-henicosaazanonanonacontane-1,81,99-tricarboxylic acid

Shipping Temperature:

cold shipment

HSN Code:

38229010

Country of Origin:

India

Smiles:

Description

D-[Ser]-11-Semaglutide is a pharmaceutical impurity reference standard related to Semaglutide, molecular formula C187H291N45O59, molecular weight 4113.64. Identified industry-wide by amino-acid sequence rather than by a CAS number. Sequence: H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-D-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-(AEEAc-AEEAc-γ-Glu-17-carboxy heptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Allas Chem Tech, a Bangalore-based manufacturer and supplier of pharmaceutical reference standards, carries this material in 50 mg packs at Rs.99000/-, supplied with a certificate of analysis and complete characterisation data.

Specifications

Field Value
Catalogue No. Pending (client SKU — not available without live-site access)
CAS No. Not assigned (standard for peptide-related substances; identified by sequence)
Amino Acid Sequence H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-D-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-(AEEAc-AEEAc-γ-Glu-17-carboxy heptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH
Chemical Name Identified industry-wide by amino-acid sequence rather than by a CAS number. Sequence: H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-D-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-(AEEAc-AEEAc-γ-Glu-17-carboxy heptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH.
Mol. Formula C187H291N45O59
Mol. Weight 4113.64
Parent API Semaglutide
Product Category Impurity Reference Standard
Pack Size 50 mg
Price Rs.99000/- per 50 mg
Stock Status Ships in 5-6 Weeks
SMILES Not published by third-party sources consulted
Shipping Ambient
HSN Code 38229010
Country of Origin India

Analytical applications

D-[Ser]-11-Semaglutide is used in analytical method development and method validation (AMV), and in Quality Control (QC) applications supporting Abbreviated New Drug Applications (ANDA) and commercial production of semaglutide.

D-amino-acid chiral-inversion impurity (position 11); well-corroborated, formula/MW identical to parent

Sequence, formula and MW confirmed by 2 independent sources: Daicel Pharma Standards and KM Pharma. No conflicts. A D-amino-acid chiral-inversion impurity at position 11 (Ser to D-Ser), part of the same degradant class as rows 249/250. Formula and MW are identical to parent Semaglutide, consistent with every other single-point D-isomer impurity in this 11-row run (244-254).

Quality control and regulatory filings

The standard supports routine QC release testing of semaglutide drug substance and drug product, and is used to generate impurity data submitted in ANDA and DMF applications. Full characterisation data accompanies every batch for direct citation in regulatory documentation.

Documentation supplied

Every order of D-[Ser]-11-Semaglutide ships with a Certificate of Analysis (COA), 1H NMR, 13C NMR, Mass/LC-MS, HPLC, FT-IR and TGA potency data. An MSDS, a Structure Elucidation Report and 2D NMR (COSY, HSQC, HMBC) are available on request.

Synonyms and alternate designations

All of the following describe the same material (CAS not yet assigned).

  • Amino-acid sequence: H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-D-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-(AEEAc-AEEAc-γ-Glu-17-carboxy heptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH

Frequently asked questions

What is the CAS number of D-[Ser]-11-Semaglutide?

D-[Ser]-11-Semaglutide does not currently have an assigned CAS Registry Number; it is identified industry-wide by amino-acid sequence rather than CAS number.

Which drug is this an impurity of?

It is a Semaglutide impurity.

What is the molecular formula and weight?

The molecular formula is C187H291N45O59 and the molecular weight is 4113.64.

Where can I buy D-[Ser]-11-Semaglutide?

Allas Chem Tech supplies it directly from our Bangalore facility. D-[Ser]-11-Semaglutide is listed at Rs.99000/- per 50 mg for a 50 mg pack; current availability per the product URL slug is ships in 5-6 weeks.

What documentation is included?

COA, MSDS, NMR, Mass, HPLC, IR and TGA potency data, with a Structure Elucidation Report available on request.

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D-[Ser]-11-Semaglutide

D-[Ser]-11-Semaglutide (INR 99000/- 50 mg, 5-6 weeks)