Dapagliflozin Carboxylic Acid Impurity (INR 15900/- 50 mg, in stock)
Catalogue No:
ACT-D011003
Common name:
(2S,3S,4R,5R,6S)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid
CAS:
1219000-66-4
Mol. Weight:
422.9
Rel. CAS No
- NA
Shipping Condition
Ambient
Product Overview
Chemical Name:
(2S,3S,4R,5R,6S)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid
Shipping Temperature:
Ambient
HSN Code:
38229010
Country of Origin:
India
Smiles:
O[C@H]1[C@@H](O[C@@H]([C@H]([C@@H]1O)O)C(O)=O)C2=CC(CC3=CC=C(C=C3)OCC)=C(C=C2)Cl
Description
Dapagliflozin Carboxylic Acid Impurity (CAS 1219000-66-4) is a pharmaceutical impurity reference standard related to dapagliflozin, molecular formula C21H23ClO7, molecular weight 422.9. Chemically (2S,3S,4R,5R,6S)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid, it carries a carboxylic acid where the finished drug carries a primary alcohol on the sugar ring, consistent with an oxidative degradation product formed at the glycoside's exocyclic hydroxymethyl group. Allas Chem Tech, a Bangalore-based manufacturer and supplier of pharmaceutical reference standards, holds this material in stock in 50 mg packs at Rs.15,900/-, supplied with a certificate of analysis and complete characterisation data.
Specifications
|
Field |
Value |
|---|---|
| Catalogue No. | ACT-D011003 |
| CAS No. | 1219000-66-4 |
| Chemical Name | (2S,3S,4R,5R,6S)-6-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid |
| Mol. Formula | C21H23ClO7 (computed from the SMILES on the live Allas page; matches the page's own displayed 422.9 closely) |
| Mol. Weight | 422.9 g/mol |
| Parent API | Dapagliflozin |
| Product Category | Impurity Reference Standard |
| Pack Size | 50 mg |
| Price | Rs.15,900/- per 50 mg |
| Stock Status | In Stock |
| SMILES | O[C@H]1[C@@H](O[C@@H]([C@H]([C@@H]1O)O)C(O)=O)C2=CC(CC3=CC=C(C=C3)OCC)=C(C=C2)Cl |
| Shipping | Ambient |
| HSN Code | 38229010 |
| Country of Origin | India |
Analytical applications
Dapagliflozin Carboxylic Acid Impurity is used in analytical method development and method validation (AMV), and in Quality Control (QC) applications supporting Abbreviated New Drug Applications (ANDA) and commercial production of dapagliflozin.
Oxidative degradation control
The carboxylic acid in place of the finished drug's own primary alcohol on the sugar ring indicates an oxidative degradation pathway, making this a stability-indicating impurity relevant to forced-degradation and shelf-life studies as well as routine synthesis QC.
Quality control and regulatory filings
The standard supports routine QC release testing of dapagliflozin drug substance and formulated tablets, and is used to generate impurity data submitted in ANDA and DMF applications. Full characterisation data accompanies every batch for direct citation in regulatory documentation.
Documentation supplied
Every order of Dapagliflozin Carboxylic Acid Impurity ships with a Certificate of Analysis (COA), 1H NMR, 13C NMR, Mass/LC-MS, HPLC, FT-IR and TGA potency data. An MSDS, a Structure Elucidation Report and 2D NMR (COSY, HSQC, HMBC) are available on request.
Synonyms and alternate designations
(2S,3S,4R,5R,6S)-6-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid
Frequently asked questions
What is the CAS number of Dapagliflozin Carboxylic Acid Impurity?
The CAS number is 1219000-66-4.
Which drug is this an impurity of?
It is a Dapagliflozin impurity. Dapagliflozin is an SGLT2 inhibitor used to treat type 2 diabetes, heart failure and chronic kidney disease.
What is the molecular formula and weight?
The molecular formula is C21H23ClO7 and the molecular weight is 422.9 g/mol.
Where can I buy Dapagliflozin Carboxylic Acid Impurity?
Allas Chem Tech supplies it directly from our Bangalore facility. It is in stock in 50 mg packs at Rs.15,900/-, shipped at ambient temperature.
What documentation is included?
COA, MSDS, NMR, Mass, HPLC, IR and TGA potency data, with a Structure Elucidation Report available on request.
