Ezetimibe Diacetate (INR 5900/- 50 mg, in stock)
Catalogue No:
ACT-E005003
Common name:
Ezetimibe Diacetate
CAS:
163380-20-9
Mol. Weight:
493.5
Rel. CAS No
- NA
Shipping Condition
Ambient
Product Overview
Chemical Name:
4-((2S,3R)-3-((S)-3-Acetoxy-3-(4-fluorophenyl)propyl)-1-(4-fluorophenyl)-4-oxoazetidin-2-yl)phenyl acetate
Shipping Temperature:
Ambient
HSN Code:
38229010
Country of Origin:
India
Smiles:
O=C1[C@@H]([C@@H](C2=CC=C(OC(C)=O)C=C2)N1C3=CC=C(F)C=C3)CC[C@@H](C4=CC=C(F)C=C4)OC(C)=O
Description
Ezetimibe Diacetate (CAS 163380-20-9) is a pharmaceutical impurity reference standard supplied by Allas Chem Tech, related to Ezetimibe. It is intended for use in analytical method validation (AMV) and routine quality control (QC) testing of Ezetimibe drug substance and drug product batches.
About This Impurity Standard
Ezetimibe Diacetate is characterised and supplied as a 50 mg reference standard pack, priced at Rs.5900/- and currently shown as In Stock on the product listing. SINGLE-SOURCE FLAG — this research pass could only confirm CAS/formula/MW via PubChem's own record (CID 10505317); PubChem's vendor cross-listing for this exact structure did not surface any of the supplier names used elsewhere in this job (only generic chemical aggregators), so treat this CAS as PubChem-sourced only pending independent supplier-page confirmation. A secondary/alternate CAS (163222-39-7) also circulates for what appears to be the identical structure in some registries — this is flagged as an open identity question in Compound-Specific Notes rather than silently picking one, and is deliberately NOT cited as a Synonyms entry, consistent with the honesty principle for unconfirmed duplicate-identity cases elsewhere in this job. Structurally, this is the bis-acetylated (both hydroxyl groups protected as acetate esters) diol-diacetate intermediate from Ezetimibe's synthetic route — MW (493.50) is exactly 84.10 higher than parent Ezetimibe (409.40), matching two acetyl additions (+2 x 42.05).
Specifications
| Specification | Detail |
| Catalogue No. | Pending (client SKU — not available without live-site access) |
| CAS Number | 163380-20-9 |
| Chemical Name | [4-[(2S,3R)-3-[(3R)-3-Acetyloxy-3-(4-fluorophenyl)propyl]-1-(4-fluorophenyl)-4-oxoazetidin-2-yl]phenyl] acetate |
| Molecular Formula | C28H25F2NO5 |
| Molecular Weight | 493.50 |
| Parent API | Ezetimibe |
| Category | Pharmaceutical Impurity Reference Standard |
| Pack Size | 50 mg |
| Price | Rs.5900/- (50 mg) |
| Stock Status | In Stock |
| SMILES | CC(=O)OC1=CC=C(C=C1)C2C(C(=O)N2C3=CC=C(C=C3)F)CCC(C4=CC=C(C=C4)F)OC(=O)C |
| Shipping | Dispatched per the lead time shown in Stock Status above |
| HSN Code | 38229010 |
| Country of Origin | India |
Analytical Applications
General Use
This reference standard supports impurity profiling, forced-degradation studies, and stability-indicating HPLC/UPLC method development and validation for Ezetimibe-based formulations, in line with ICH Q3A/Q3B impurity qualification requirements.
Compound-Specific Notes
FLAG: single-source corroboration (PubChem record only; no named-supplier cross-listing found for this exact CAS). A secondary CAS (163222-39-7) also appears in some registries for what looks like the same structure — this is an open identity question, deliberately not promoted to a Synonyms entry. Clean mass-balance check (+2 acetyl groups, +84.10 vs parent Ezetimibe) supports the structural identity regardless.
Quality Control
Use of a well-characterized Ezetimibe Diacetate reference standard supports accurate peak identification and quantitation during routine QC release testing and stability studies for Ezetimibe drug substance and finished-dose batches.
Documentation Supplied
Each unit of Ezetimibe Diacetate ships with a Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS), and supporting HPLC chromatographic/analytical data confirming the stated identity and purity.
Synonyms and Alternate Designations
- [4-[(2S,3R)-3-[(3R)-3-Acetyloxy-3-(4-fluorophenyl)propyl]-1-(4-fluorophenyl)-4-oxoazetidin-2-yl]phenyl] acetate (full IUPAC systematic name, used as the alternate designation; the secondary CAS 163222-39-7 some registries show for this structure is an open identity question, not a confirmed alternate name — see Open Items)
Frequently Asked Questions
What is Ezetimibe Diacetate used for?
Ezetimibe Diacetate is used as a pharmaceutical impurity reference standard for analytical method validation (AMV) and routine quality control testing of Ezetimibe and its formulations.
Is Ezetimibe Diacetate available in stock?
Ezetimibe Diacetate is listed at Rs.5900/- (50 mg) for a 50 mg pack; current availability is shown as in stock on the Allas Chem Tech product page.
Does Ezetimibe Diacetate have a CAS number?
The CAS Registry Number for Ezetimibe Diacetate is 163380-20-9.
What documentation is supplied with Ezetimibe Diacetate?
Each unit of Ezetimibe Diacetate ships with a Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS), and supporting HPLC analytical data.
