Ezetimibe Ketone (INR 12900/- 50 mg, in stock)
Catalogue No:
ACT-E005004
Common name:
Ezetimibe Ketone
CAS:
191330-56-0
Mol. Weight:
407.4
Rel. CAS No
- NA
Shipping Condition
Ambient
Product Overview
Chemical Name:
((3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)azetidin-2-one)
Shipping Temperature:
Ambient
HSN Code:
38229010
Country of Origin:
India
Smiles:
OC(C=C1)=CC=C1[C@H]([C@H](C2=O)CCC(C3=CC=C(F)C=C3)=O)N2C4=CC=C(F)C=C4
Description
Ezetimibe Ketone (CAS 191330-56-0) is a pharmaceutical impurity reference standard supplied by Allas Chem Tech, related to Ezetimibe. It is intended for use in analytical method validation (AMV) and routine quality control (QC) testing of Ezetimibe drug substance and drug product batches.
About This Impurity Standard
Ezetimibe Ketone is characterised and supplied as a 50 mg reference standard pack, priced at Rs.12900/- and currently shown as In Stock on the product listing. CAS confirmed by 4 independent sources (Veeprho, BOC Sciences, Clearsynth, MedChemExpress) — the best-corroborated row in this batch. This is a direct oxidation product of Ezetimibe at its benzylic secondary-alcohol side chain (secondary alcohol to ketone), keeping the azetidinone core intact — MW (407.40) is exactly 2.00 lower than parent Ezetimibe (409.40), consistent with loss of H2 on oxidation. Also known as Ezetimibe's own human metabolite "SCH 57871."
Specifications
| Specification | Detail |
| Catalogue No. | Pending (client SKU — not available without live-site access) |
| CAS Number | 191330-56-0 |
| Chemical Name | (3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)azetidin-2-one |
| Molecular Formula | C24H19F2NO3 |
| Molecular Weight | 407.40 |
| Parent API | Ezetimibe |
| Category | Pharmaceutical Impurity Reference Standard |
| Pack Size | 50 mg |
| Price | Rs.12900/- (50 mg) |
| Stock Status | In Stock |
| SMILES | C1=CC(=CC=C1C2C(C(=O)N2C3=CC=C(C=C3)F)CCC(=O)C4=CC=C(C=C4)F)O |
| Shipping | Dispatched per the lead time shown in Stock Status above |
| HSN Code | 38229010 |
| Country of Origin | India |
Analytical Applications
General Use
This reference standard supports impurity profiling, forced-degradation studies, and stability-indicating HPLC/UPLC method development and validation for Ezetimibe-based formulations, in line with ICH Q3A/Q3B impurity qualification requirements.
Compound-Specific Notes
No conflicts across 4 sources — strongest corroboration in this batch. Clean oxidation-product relationship to parent Ezetimibe (MW exactly -2.00 vs parent, secondary alcohol to ketone). Also the parent drug's own metabolite "SCH 57871."
Quality Control
Use of a well-characterized Ezetimibe Ketone reference standard supports accurate peak identification and quantitation during routine QC release testing and stability studies for Ezetimibe drug substance and finished-dose batches.
Documentation Supplied
Each unit of Ezetimibe Ketone ships with a Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS), and supporting HPLC chromatographic/analytical data confirming the stated identity and purity.
Synonyms and Alternate Designations
- SCH 57871 (confirmed research/metabolite code name — this is Ezetimibe's own human metabolite, stated by the sourced material)
Frequently Asked Questions
What is Ezetimibe Ketone used for?
Ezetimibe Ketone is used as a pharmaceutical impurity reference standard for analytical method validation (AMV) and routine quality control testing of Ezetimibe and its formulations.
Is Ezetimibe Ketone available in stock?
Ezetimibe Ketone is listed at Rs.12900/- (50 mg) for a 50 mg pack; current availability is shown as in stock on the Allas Chem Tech product page.
Does Ezetimibe Ketone have a CAS number?
The CAS Registry Number for Ezetimibe Ketone is 191330-56-0.
What documentation is supplied with Ezetimibe Ketone?
Each unit of Ezetimibe Ketone ships with a Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS), and supporting HPLC analytical data.
