Ezetimibe Tetrahydropyran Analog (INR 9900/- 50 mg, in stock)
Catalogue No:
ACT-E005005
Common name:
Ezetimibe Tetrahydropyran Analog
CAS:
1296129-15-1
Mol. Weight:
409.4
Rel. CAS No
- NA
Shipping Condition
Ambient
Product Overview
Chemical Name:
((2R,3R,6S)-N,6-bis(4-fluorophenyl)-2-(4-hydroxyphenyl)tetrahydro-2H-pyran-3-carboxamide)
Shipping Temperature:
Ambient
HSN Code:
38229010
Country of Origin:
India
Smiles:
O=C([C@H]1[C@H](C2=CC=C(O)C=C2)O[C@H](C3=CC=C(F)C=C3)CC1)NC4=CC=C(F)C=C4
Description
Ezetimibe Tetrahydropyran Analog (CAS 1050631-82-7) is a pharmaceutical impurity reference standard supplied by Allas Chem Tech, related to Ezetimibe. It is intended for use in analytical method validation (AMV) and routine quality control (QC) testing of Ezetimibe drug substance and drug product batches.
About This Impurity Standard
Ezetimibe Tetrahydropyran Analog is characterised and supplied as a 50 mg reference standard pack, priced at Rs.9900/- and currently shown as In Stock on the product listing. CAS confirmed by 2 independent sources (Veeprho, BOC Sciences, cross-referenced via PubChem's own aggregated vendor catalog data for this exact structure, since this research pass could not reach general web search or open supplier pages directly and relied on PubChem's PUG-View endpoints and its internal cross-listing of depositing suppliers — flagged as slightly weaker than direct supplier-page confirmation). Opens the 4-row Ezetimibe family for this batch. Structurally, this is not an oxidation or acetylation variant but a ring-rearranged isomer of Ezetimibe itself — the beta-lactam (azetidinone) ring is opened and the carbon chain instead cyclizes through the pyran oxygen into an open-chain carboxamide fused to a tetrahydropyran ring, giving it the identical molecular formula and MW (409.40) as parent Ezetimibe despite being a structurally distinct cyclization side-product from the azetidinone-forming synthetic step. Copy pairs MW with CAS/structure rather than stating MW alone.
Specifications
| Specification | Detail |
| Catalogue No. | Pending (client SKU — not available without live-site access) |
| CAS Number | 1050631-82-7 |
| Chemical Name | N,6-Bis(4-fluorophenyl)-2-(4-hydroxyphenyl)tetrahydro-2H-pyran-3-carboxamide |
| Molecular Formula | C24H21F2NO3 |
| Molecular Weight | 409.40 |
| Parent API | Ezetimibe |
| Category | Pharmaceutical Impurity Reference Standard |
| Pack Size | 50 mg |
| Price | Rs.9900/- (50 mg) |
| Stock Status | In Stock |
| SMILES | C1CC(OC(C1C(=O)NC2=CC=C(C=C2)F)C3=CC=C(C=C3)F)C4=CC=C(C=C4)O |
| Shipping | Dispatched per the lead time shown in Stock Status above |
| HSN Code | 38229010 |
| Country of Origin | India |
Analytical Applications
General Use
This reference standard supports impurity profiling, forced-degradation studies, and stability-indicating HPLC/UPLC method development and validation for Ezetimibe-based formulations, in line with ICH Q3A/Q3B impurity qualification requirements.
Compound-Specific Notes
No conflicts across 2 sources (corroborated via PubChem's vendor cross-listing methodology, flagged as slightly weaker than direct supplier-page confirmation). Isomer-coincidence flag: identical formula/MW to parent Ezetimibe itself (both C24H21F2NO3, 409.40) — distinct ring-rearranged compound, always pair MW with CAS/structure in copy.
Quality Control
Use of a well-characterized Ezetimibe Tetrahydropyran Analog reference standard supports accurate peak identification and quantitation during routine QC release testing and stability studies for Ezetimibe drug substance and finished-dose batches.
Documentation Supplied
Each unit of Ezetimibe Tetrahydropyran Analog ships with a Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS), and supporting HPLC chromatographic/analytical data confirming the stated identity and purity.
Synonyms and Alternate Designations
- Ezetimibe Impurity 60 (confirmed alternate catalog name for the same CAS, stated by the sourced material)
- Ezetimibe Cyclic Ether Impurity (confirmed alternate descriptive name for the same CAS, stated by the sourced material)
Frequently Asked Questions
What is Ezetimibe Tetrahydropyran Analog used for?
Ezetimibe Tetrahydropyran Analog is used as a pharmaceutical impurity reference standard for analytical method validation (AMV) and routine quality control testing of Ezetimibe and its formulations.
Is Ezetimibe Tetrahydropyran Analog available in stock?
Ezetimibe Tetrahydropyran Analog is listed at Rs.9900/- (50 mg) for a 50 mg pack; current availability is shown as in stock on the Allas Chem Tech product page.
Does Ezetimibe Tetrahydropyran Analog have a CAS number?
The CAS Registry Number for Ezetimibe Tetrahydropyran Analog is 1050631-82-7.
What documentation is supplied with Ezetimibe Tetrahydropyran Analog?
Each unit of Ezetimibe Tetrahydropyran Analog ships with a Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS), and supporting HPLC analytical data.
