Tolvaptan Impurity 55 (INR 29900/- 50 mg , in stock)
Catalogue No:
ACT-T014001
Common name:
1-(4-Amino-2-methylbenzoyl)-7-chloro-2,3-dihydro-1H-benzo[b]azepin-5-yl 4-amino-2-methylbenzoate
CAS:
1580889-35-5
Mol. Weight:
461.9
Rel. CAS No
- NA
Shipping Condition
Ambient
Product Overview
Chemical Name:
1-(4-Amino-2-methylbenzoyl)-7-chloro-2,3-dihydro-1H-benzo[b]azepin-5-yl 4-amino-2-methylbenzoate
Shipping Temperature:
Ambient
HSN Code:
38229010
Country of Origin:
India
Smiles:
ClC1=CC=C(N(C(C2=CC=C(N)C=C2C)=O)CCC=C3OC(C4=CC=C(N)C=C4C)=O)C3=C1
Description
Tolvaptan Impurity 55 (CAS 1580889-35-5) is a pharmaceutical impurity reference standard related to tolvaptan, molecular formula C26H24ClN3O3, molecular weight 461.9. Chemically 1-(4-Amino-2-methylbenzoyl)-7-chloro-2,3-dihydro-1H-benzo[b]azepin-5-yl 4-amino-2-methylbenzoate, it retains both amino-methylbenzoyl-type groups of tolvaptan's own structure but with an ester linkage in place of the finished drug's benzamide, indicating an O- rather than N-acylated regioisomer. Allas Chem Tech, a Bangalore-based manufacturer and supplier of pharmaceutical reference standards, holds this material in stock in 50 mg packs at Rs.29,900/-, supplied with a certificate of analysis and complete characterisation data.
Specifications
| Field | Value |
|---|---|
| Catalogue No. | ACT-T014001 |
| CAS No. | 1580889-35-5 |
| Chemical Name | 1-(4-Amino-2-methylbenzoyl)-7-chloro-2,3-dihydro-1H-benzo[b]azepin-5-yl 4-amino-2-methylbenzoate |
| Mol. Formula | C26H24ClN3O3 (computed from the SMILES on the live Allas page; matches the page's own displayed 461.9 closely) |
| Mol. Weight | 461.9 g/mol |
| Parent API | Tolvaptan |
| Product Category | Impurity Reference Standard |
| Pack Size | 50 mg |
| Price | Rs.29,900/- per 50 mg |
| Stock Status | In Stock |
| SMILES | ClC1=CC=C(N(C(C2=CC=C(N)C=C2C)=O)CCC=C3OC(C4=CC=C(N)C=C4C)=O)C3=C1 |
| Shipping | Ambient |
| HSN Code | 38229010 |
| Country of Origin | India |
Analytical applications
Tolvaptan Impurity 55 is used in analytical method development and method validation (AMV), and in Quality Control (QC) applications supporting Abbreviated New Drug Applications (ANDA) and commercial production of tolvaptan.
O-acylated regioisomer process control
The ester linkage in place of tolvaptan's own amide linkage indicates an O- rather than N-acylation occurring during the same synthetic step, making this a process-related regioisomeric impurity.
Quality control and regulatory filings
The standard supports routine QC release testing of tolvaptan drug substance and formulated tablets, and is used to generate impurity data submitted in ANDA and DMF applications. Full characterisation data accompanies every batch for direct citation in regulatory documentation.
Documentation supplied
Every order of Tolvaptan Impurity 55 ships with a Certificate of Analysis (COA), 1H NMR, 13C NMR, Mass/LC-MS, HPLC, FT-IR and TGA potency data. An MSDS, a Structure Elucidation Report and 2D NMR (COSY, HSQC, HMBC) are available on request.
Synonyms and alternate designations
1-(4-Amino-2-methylbenzoyl)-7-chloro-2,3-dihydro-1H-benzo[b]azepin-5-yl
4-amino-2-methylbenzoate
Frequently asked questions
What is the CAS number of Tolvaptan Impurity 55?
The CAS number is 1580889-35-5.
Which drug is this an impurity of?
It is a Tolvaptan impurity. Tolvaptan is a vasopressin receptor antagonist used to treat hyponatremia and polycystic kidney disease.
What is the molecular formula and weight?
The molecular formula is C26H24ClN3O3 and the molecular weight is 461.9 g/mol.
Where can I buy Tolvaptan Impurity 55?
Allas Chem Tech supplies it directly from our Bangalore facility. It is in stock in 50 mg packs at Rs.29,900/-, shipped at ambient temperature.
What documentation is included?
COA, MSDS, NMR, Mass, HPLC, IR and TGA potency data, with a Structure Elucidation Report available on request.
