Tolvaptan Impurity 72 (INR 15900/- 50 mg, in stock)
Catalogue No:
ACT-T014002
Common name:
7-Chloro-1-(2-methyl-4-nitrobenzoyl)-2,3-dihydro-1H-benzo[b]azepin-5-yl 2-methyl-4-nitrobenzoate
CAS:
NA
Mol. Weight:
521.9
Rel. CAS No
- NA
Shipping Condition
Ambient
Product Overview
Chemical Name:
7-Chloro-1-(2-methyl-4-nitrobenzoyl)-2,3-dihydro-1H-benzo[b]azepin-5-yl 2-methyl-4-nitrobenzoate
Shipping Temperature:
Ambient
HSN Code:
38229010
Country of Origin:
India
Smiles:
O=C(OC1=CCCN(C(C2=CC=C([N+]([O-])=O)C=C2C)=O)C3=CC=C(Cl)C=C31)C4=CC=C([N+]([O-])=O)C=C4C
Description
Tolvaptan Impurity 72 is a pharmaceutical impurity reference standard related to tolvaptan, molecular formula C26H20ClN3O7, molecular weight 521.9; CAS number not currently assigned. Chemically 7-Chloro-1-(2-methyl-4-nitrobenzoyl)-2,3-dihydro-1H-benzo[b]azepin-5-yl 2-methyl-4-nitrobenzoate, it carries two nitro-substituted benzoyl groups in place of tolvaptan's own single amino-substituted benzoyl and benzamide groups, consistent with an incompletely reduced synthetic intermediate. Allas Chem Tech, a Bangalore-based manufacturer and supplier of pharmaceutical reference standards, holds this material in stock in 50 mg packs at Rs.15,900/-, supplied with a certificate of analysis and complete characterisation data.
Specifications
| Field | Value |
|---|---|
| Catalogue No. | ACT-T014002 |
| CAS No. | Not Assigned |
| Chemical Name | 7-Chloro-1-(2-methyl-4-nitrobenzoyl)-2,3-dihydro-1H-benzo[b]azepin-5-yl 2-methyl-4-nitrobenzoate |
| Mol. Formula | C26H20ClN3O7 (computed from the SMILES on the live Allas page; matches the page's own displayed 521.9 exactly) |
| Mol. Weight | 521.9 g/mol |
| Parent API | Tolvaptan |
| Product Category | Impurity Reference Standard |
| Pack Size | 50 mg |
| Price | Rs.15,900/- per 50 mg |
| Stock Status | In Stock |
| SMILES | O=C(OC1=CCCN(C(C2=CC=C([N+]([O-])=O)C=C2C)=O)C3=CC=C(Cl)C=C31)C4=CC=C([N+]([O-])=O)C=C4C |
| Shipping | Ambient |
| HSN Code | 38229010 |
| Country of Origin | India |
Analytical applications
Tolvaptan Impurity 72 is used in analytical method development and method validation (AMV), and in Quality Control (QC) applications supporting Abbreviated New Drug Applications (ANDA) and commercial production of tolvaptan.
Nitro-intermediate process control
Carrying two nitro-substituted benzoyl groups where the finished drug carries amino-substituted equivalents, this impurity indicates incomplete nitro-to-amino reduction during synthesis, placing it earlier in the tolvaptan route than a degradation impurity.
Quality control and regulatory filings
The standard supports routine QC release testing of tolvaptan drug substance and formulated tablets, and is used to generate impurity data submitted in ANDA and DMF applications. Full characterisation data accompanies every batch for direct citation in regulatory documentation.
Documentation supplied
Every order of Tolvaptan Impurity 72 ships with a Certificate of Analysis (COA), 1H NMR, 13C NMR, Mass/LC-MS, HPLC, FT-IR and TGA potency data. An MSDS, a Structure Elucidation Report and 2D NMR (COSY, HSQC, HMBC) are available on request.
Synonyms and alternate designations
7-Chloro-1-(2-methyl-4-nitrobenzoyl)-2,3-dihydro-1H-benzo[b]azepin-5-yl 2-methyl-4-nitrobenzoate
Frequently asked questions
What is the CAS number of Tolvaptan Impurity 72?
No CAS number is currently assigned to this material.
Which drug is this an impurity of?
It is a Tolvaptan impurity. Tolvaptan is a vasopressin receptor antagonist used to treat hyponatremia and polycystic kidney disease.
What is the molecular formula and weight?
The molecular formula is C26H20ClN3O7 and the molecular weight is 521.9 g/mol.
Where can I buy Tolvaptan Impurity 72?
Allas Chem Tech supplies it directly from our Bangalore facility. It is in stock in 50 mg packs at Rs.15,900/-, shipped at ambient temperature.
What documentation is included?
COA, MSDS, NMR, Mass, HPLC, IR and TGA potency data, with a Structure Elucidation Report available on request.
