Varenicline Dioxo Impurity (INR 19900/- 50 mg, in stock)
Catalogue No:
ACT-V003002
Common name:
Varenicline Dioxo Impurity
CAS:
357424-07-8
Mol. Weight:
243.3
Rel. CAS No
Shipping Condition
Ambient
Product Overview
Chemical Name:
4,6,7,8,9,10-Hexahydro-1H-6,10-methanoazepino[4,5-g]quinoxaline-2,3-dione
Shipping Temperature:
Ambient
HSN Code:
38229010
Country of Origin:
India
Smiles:
O=C1C(NC(C=C(C2CNCC3C2)C3=C4)=C4N1)=O
Description
Varenicline Dioxo Impurity (CAS 357424-07-8) is a pharmaceutical impurity reference standard supplied by Allas Chem Tech, related to Varenicline. It is intended for use in analytical method validation (AMV) and routine quality control (QC) testing of Varenicline drug substance and drug product batches.
About This Impurity Standard
UPGRADED FROM SINGLE-VENDOR TO CROSS-CONFIRMED VIA AN ADDITIONAL WEBSEARCH PASS THIS ROUND. The old doc flagged this as single-vendor (Veeprho, HCl salt, no CAS). A fresh search this round independently located SynZeal's dedicated page for "Varenicline Dioxo Impurity" (freebase), which publishes CAS 357424-07-8 -- matching Veeprho's name and the underlying formula/MW family exactly (freebase vs. HCl-salt mass difference accounts for the MW gap). This resolves the prior no-CAS gap with a genuine 2-vendor cross-confirmation.
Specifications
| Specification | Detail |
| Catalogue No. | Pending (client SKU — not available without live-site access) |
| CAS Number | 357424-07-8 |
| Chemical Name | 4,6,7,8,9,10-Hexahydro-1H-6,10-methanoazepino[4,5-g]quinoxaline-2,3-dione (freebase) -- aka Varenicline DP-I Impurity or Varenicline Oxidative Impurity; also sold by Veeprho as the HCl salt |
| Molecular Formula | C13H13N3O2 (freebase); as HCl salt per Veeprho |
| Molecular Weight | 243.3 (freebase, SynZeal); 279.72 as HCl salt (Veeprho) |
| Parent API | Varenicline |
| Category | Pharmaceutical Impurity Reference Standard |
| Pack Size | 50 mg |
| Price | Rs.19900/- (50 mg) |
| Stock Status | In Stock |
| SMILES | Not published by any third-party source consulted |
| Shipping | Dispatched per the lead time shown in Stock Status above |
| HSN Code | 38229010 |
| Country of Origin | India |
Analytical Applications
General Use
This reference standard supports impurity profiling, forced-degradation studies, and stability-indicating HPLC/UPLC method development and validation for Varenicline-based formulations, in line with ICH Q3A/Q3B impurity qualification requirements.
Compound-Specific Notes
Name/formula cross-confirmed across 2 independent named vendors (Veeprho, SynZeal) via an additional WebSearch pass this round -- high confidence. SynZeal's freebase CAS (357424-07-8) resolves the prior no-CAS gap; Veeprho's listing is the HCl salt form.
Quality Control
Use of a well-characterized Varenicline Dioxo Impurity reference standard supports accurate peak identification and quantitation during routine QC release testing and stability studies for Varenicline drug substance and finished-dose batches.
Documentation Supplied
Each unit of Varenicline Dioxo Impurity ships with a Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS), and supporting HPLC chromatographic/analytical data confirming the stated identity and purity.
Synonyms and Alternate Designations
- Varenicline DP-I Impurity / Varenicline Oxidative Impurity, HCl salt (alternate designation given by Veeprho for the HCl-salt form; freebase form independently cross-confirmed by SynZeal under CAS 357424-07-8)
Frequently Asked Questions
What is Varenicline Dioxo Impurity used for?
Varenicline Dioxo Impurity is used as a pharmaceutical impurity reference standard for analytical method validation (AMV) and routine quality control testing of Varenicline and its formulations.
Is Varenicline Dioxo Impurity available in stock?
Varenicline Dioxo Impurity is listed at Rs.19900/- (50 mg) for a 50 mg pack; current availability is shown as in stock on the Allas Chem Tech product page.
Does Varenicline Dioxo Impurity have a CAS number?
The CAS Registry Number for Varenicline Dioxo Impurity is 357424-07-8.
What documentation is supplied with Varenicline Dioxo Impurity?
Each unit of Varenicline Dioxo Impurity ships with a Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS), and supporting HPLC analytical data.
